The Kansas City defense has been the NFL’s best, holding each opponent to less than 17 points. Can they contain Peyton Manning and the Broncos? (AP Photo/ Bill Wippert)

Frank Gore and the 49ers have steamrolled their last five opponents, winning by an average of 23 points. Will their dominance continue over the streaking Panthers? (Photo by Jamie McDonald/Getty Images)

As injuries to key players mount, the Packers continue to win. Will they make it five straight Monday? (Photo by Adam Bettcher/Getty Images)

The Steelers are winners of two straight. With a relatively soft schedule the rest of the way, is there hope for the playoffs?

Steve Smith and the Panthers have won two straight and appear to have found some offensive consistency (finally). Will it continue? (AP Photo/Bob Leverone)

Peyton Manning’s homecoming kicked off with a slap to the face from Colts owner Jim Irsay. Will Manning move to 7-0 at the Colts expense? Elsewhere, Reggie Bush is really […]

Russell Wilson helped turn Seattle from laughing stock to contender. The Cardinals are in desperate need of a Russell Wilson of their own. (AP Photo/Elaine Thompson)

Though lacking talent and depleted by injuries, Bill Belichick has the Patriots near the top of the AFC (again). How long can they survive? (AP Photo/Tom Uhlman)

The Giants are epically bad – like Jacksonville Jaguars bad. The Bears may not be very good either. Who stinks less Thursday night? (AP Photo/Nam Y. Huh)

Eli Manning and the Giants are struggling mightily. The Eagles and their terrible defense may be just the cure New York needs. (AP Photo/Charlie Riedel)

The Chicago Bears have a new coach and new offense but their bread-and-butter is still the defense. Can it derail Calvin Johnson and the Lions to maintain first place in […]

Even at 2-0 the Texans and Arian Foster are searching for their lost mojo. Also, defending the Trent Richardson trade as a reasonable move by Cleveland. (Photo by Scott Halleran/Getty Images)

Who says you can’t go home? Andy Reid returns to Philadelphia to meet Chip Kelly’s offense… and benefit from a complete lack of defense. The Eagles are in trouble. (Photo by […]

There’s a showdown in Seattle you do not want to miss. Colin Kaepernick and his apparently unending skill set will be in attendance. (Photo by Jeff Gross/Getty Images)